MH - this is the response I got from forwarding your right up, research, questions.

"HI Mark,



Firstly we do not supply ImunoZen to Shibumi anymore.



Thanks for the email on the list of threads on the blog.



There are so many questions in this that it would take me ages to respond. I will respond quickly by saying that whoever mentioned the Now product Cholesatin didn’t read the label as it mentions there are citrus pectin in the product, but I didn’t see any in Now’s ingredient label. If there are citrus pectin in the product it is a source of dietary fibre, a gelling agent and little if any nutritional value. Citrus pectin known as a-D-galaclosyluronic acid would be a compound that would not work well with the sterols, it has a carboxyl group in the structure. Citrus pectin would also be destroyed by stomach acids.



The company “Now” mentions sterolins which we have found no research to support sterol ins having any therapeutic relevance. This sub-structure of sterols is not referenced correctly. A reliable source for organic compounds would be the Merck Pharmacopia, and it does not refer to “sterolins” but rather to the more accurate name of beta-sitosterol glucocide. (sugar)



Our study at Guelph was done on a small covert of people on a short period of time as it runs a higher degree of risk when done on small populations. Most companies will get a higher percentage of success if they do these studies on large population and over longer periods of time. It was also an investigation of potential immune/allergy parameters.



Hope you are well and keeping fit, which I am sure you are.

Cheers

Jack"