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Its my understanding that 75% of genetic potential after the age of 45 is determined by what you do up to the age of 45.
Genetics in a way is huge but genetic expression (genes turning on and off, how genes act etc) is so determined by the genes environment which is the cell. The cell gets its info from the receptor sites on its surface. They take in neuropetides (informational chemicals etc)... what comes into the body from food, air, skin etc and also the chemicals released with thoughts and emotions. What research has found (Candace Pert and Bruce Lipton for example) is that the same receptor sites and the same neuropeptides are found everywhere in the body.
That means the insulin response to food affects the brain as well and the chemicals released with feelings of anger or joy also find there way to the heart, immune system, lungs, muscles etc etc etc
No the "grandfather cells" teach the baby cells whats what and how to act (all the cells are replaced in the body all the time - I think the vast majority are replaced within 6 years). So if you change the incoming information you get a different out come.
I think thats pretty cool and gives some insight to the healing potential of the body.
chronological age can get younger as we live healthier etc (so far there are still limits of course)